Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC AT7519 Hydrochloride 902135-91-5 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A31975.1
AT7519 Hydrochloride (CAS 902135-91-5) is a small-molecule inhibitor of cyclin-dependent kinases (CDKs) which are critical regulators of cell proliferation division and apoptosis in eukaryotic cells By targeting multiple CDKs including CDK1 and CDK2 AT7519 induces cell cycle arrest and apoptosis in various human tumor cell lines demonstrating inhibitory activity with IC50 values ranging from 40 to 940 nmol/L In preclinical studies it suppressed tumor growth in xenograft models and promoted tumor cell apoptosis AT7519 is under clinical evaluation for the treatment of refractory solid tumors supporting its utility in cancer research and drug development
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?