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Medchemexpress LLC AT9283 | 896466-04-9 | 99.7% | C19H23N7O2 | 200 MG
SDP

Supplier:  Medchemexpress LLC HY50514200MG

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AT9283 is a multi-targeted kinase inhibitor with potent activity against Aurora A/B, JAK2/3, Abl (T315I), and Flt3 (IC50s 1-30 nM). It has been shown to inhibit the growth and survival of various solid tumors both in vitro and in vivo. This product is intended for research use only.

  • Potent multi-targeted kinase inhibitor
  • Active against Aurora A/B, JAK2/3, Abl (T315I), and Flt3
  • Inhibits growth and survival of various solid tumors
  • Induces polyploid phenotype and apoptosis in certain cancer cell lines
  • Shows significant tumor growth inhibition in xenograft models
  • Enhances survival in mouse xenograft models of mantle cell lymphoma

Catalog No. 50-003-58811


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