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Medchemexpress LLC Ataluren | 775304-57-9 | 284.24 | 200 MG
SDP

Catalog No. 5000366215
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Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor. It is a new chemical entity that selectively induces ribosomal readthrough of premature but not normal termination codons. This action helps prevent the cell from producing a full-length CFTR protein in vitro and promotes dystrophin production in vivo.

  • Selectively induces ribosomal readthrough of premature but not normal termination codons
  • Helps prevent the cell from producing a full-length CFTR protein
  • Promotes dystrophin production in primary muscle cells
  • Rescues striated muscle function in mdx mice
  • Well tolerated in animals

Catalog No. 50-003-66215 Supplier Medchemexpress LLC Supplier No. 200MGHY14832
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Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor. It is a new chemical entity that selectively induces ribosomal readthrough of premature but not normal termination codons. This action helps prevent the cell from producing a full-length CFTR protein in vitro and promotes dystrophin production in vivo.

  • Selectively induces ribosomal readthrough of premature but not normal termination codons
  • Helps prevent the cell from producing a full-length CFTR protein
  • Promotes dystrophin production in primary muscle cells
  • Rescues striated muscle function in mdx mice
  • Well tolerated in animals

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