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Medchemexpress LLC ATIC-IN-1 acetate | 3067165-96-9 | C23H37N7O7 | 50 MG
Supplier: Medchemexpress LLC HY150252A50MG
ATIC-IN-1 acetate is an inhibitor that targets Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM. ATIC catalyzes de novo purine biosynthesis, and its dimerization is crucial for AICAR transformylase activity. This inhibitor demonstrates anti-tumor activity by reducing cell numbers and cell division rates and inhibits the proliferation of MCF-7 cells.
- Targets ATIC dimerization with a Ki value of 685 nM
- Inhibits proliferation of MCF-7 cells
- Reduces cell numbers and cell division rates
- Suitable for studying respiratory diseases, cancer, pulmonary disease, and lung fibrosis
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