Cayman Chemical AtIpamezole 100mg

Supplier:  Cayman Chemical 34289100 MG

A 5-HT2 agonist stimulates increases in intracellular calcium levels in CHO-K1 cells expressing human 5-HT2A 5-HT2B and 5-HT2C (EC50s 447 0.9 and 32 nM respectively) selective for human 5-HT2A and 5-HT2C (Kis 32 and 1 nM respectively) over human 5-HT1A 5-HT1D 5-HT6 and 5-HT7 rat 5-HT1B and 5-HT3 and guinea pig 5-HT4 receptors (Kis ≥1995 nM) as well as adenosine A1 and A2 histamine H1-3 dopamine D1-5 a1- a2- and B1-adrenergic M1-5 muscarinic nicotinic kainate AMPA and - - and K-opioid receptors (IC50s 1000 nM) but does bind to B2-adrenergic receptors (IC50 251 nM) increases plasma levels of corticosterone oxytocin and prolactin in rats (ED50s 2.43 4.19 and 4.03 mg/kg respectively)

Catalog No. 50-294-8799