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Atiprimod dihydrochloride, Tocris Bioscience™

Catalog No. 458010
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Catalog No. Quantity
45-801-0 10 mg
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Catalog No. 45-801-0 Supplier R&D Systems Supplier No. 4580/10
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Description

JAK2 inhibitor

JAK2 inhibitor (IC50 = 397 nM). Also inhibits STAT3 and STAT5 phosphorylation. Inhibits cell growth and induces apoptosis in cells expressing the JAK2V617F mutation.

Chemical Identifiers

CAS 130065-61-1
Molecular Formula C22H46Cl2N2
Molecular Weight (g/mol) 409.524
InChI Key MOUZYBYTICOTFQ-UHFFFAOYSA-N
Synonym atiprimod dihydrochloride, atiprimod dihydrochloride usan, atiprimod hcl, atiprimod hydrochloride, 2-3-diethylamino propyl-8,8-dipropyl-2-azaspiro 4.5 decane dihydrochloride, 2-azaspiro 4.5 decane-2-propanamine n,n-diethyl-8,8-dipropyl-, dihydrochloride, 2-azaspiro 4.5 decane-2-propanamine, n,n-diethyl-8,8-dipropyl-, dihydrochloride, 3-8,8-dipropyl-3-azaspiro 4.5 decan-3-yl-n,n-diethylpropan-1-amine dihydrochloride, n,n-diethyl-8,8-dipropyl-2-azaspiro 4.5 decane-2-propanamine dihydrochloride
PubChem CID 166556
IUPAC Name 3-(8,8-dipropyl-2-azaspiro[4.5]decan-2-yl)-N,N-diethylpropan-1-amine;dihydrochloride
SMILES CCCC1(CCC2(CC1)CCN(C2)CCCN(CC)CC)CCC.Cl.Cl

Specifications

Quantity 10 mg
Formula Weight 409.52
Chemical Name or Material Atiprimod dihydrochloride

Safety and Handling

Recommended Storage Desiccate at RT
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