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Medchemexpress LLC Atorvastatin epoxy tetrahydrofuran impurity | 873950-19-7 | 449.47 | 25 MG
Supplier: Medchemexpress LLC 25MGHY136185
Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation product of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, which has the ability to effectively decrease blood lipids. Atorvastatin treatment decreases apoptosis of myocardial cells by down-regulating GRP78, caspase-12 and CHOP expression in myocardial cells after myocardial infarction. The endoplasmic reticulum (ER) stress is activated in response to heart failure and angiotensin II (Ang II) stimulation.
- Impurity isolated oxidative degradation product
- Orally active HMG-CoA reductase inhibitor
- Effectively decreases blood lipids
- Decreases apoptosis of myocardial cells
- Down-regulates GRP78, caspase-12 and CHOP expression
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