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Medchemexpress LLC Atorvastatin (hemicalcium salt) | 134523-03-8 | 99.9% | 577.67 | 500 MG
Supplier: Medchemexpress LLC HY17379500MG
Atorvastatin hemicalcium salt is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor with blood-brain barrier permeability. It effectively decreases blood lipids and inhibits human SV-SMC proliferation and invasion. This compound reduces apoptosis of myocardial cells by down-regulating GRP78, caspase-12, and CHOP expression, and activates endoplasmic reticulum stress in response to heart failure and angiotensin II stimulation.
- Orally active HMG-CoA reductase inhibitor
- Blood-brain barrier permeable
- Decreases blood lipids
- Inhibits SV-SMC proliferation and invasion
- Reduces apoptosis of myocardial cells
- Activates endoplasmic reticulum stress response
- Inhibits proinflammatory cytokines
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