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Apexbio Technology LLC Atosiban acetate 914453-95-5 50mg
Supplier: Apexbio Technology LLC B363150
Atosiban acetate (CAS 914453-95-5) is a synthetic peptide functioning as a dual antagonist of the oxytocin receptor (OTR) and vasopressin receptors (V1aR V1bR V2R) It exhibits high affinity for human OTR (pKi 7 9) and V1aR (pKi 9 8) and effectively inhibits cell proliferation in MDCK and HEK293 cells stably expressing human OTR with IC50 values of 15 4 nM and 20 8 nM respectively In preclinical models Atosiban acetate suppresses uterine contractions and delays preterm labor Its application in research includes studies of receptor-mediated signaling uterine contractility and biased agonism Due to its peptide nature it is not suitable for oral or long-term use
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