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Cayman Chemical AtractylenolIde III 10mg
SDP

Supplier:  Cayman Chemical 2491110 MG

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A cereblon modulator with an IC50 value of 60 nM in a competitive TR-FRET assay has a higher affinity for cereblon than the related modulators lenalidomide (IC50 1500 nM) and pomalidomide (IC50 1200 nM) in the same assay has a greater potency for degradation of the CRL4 complex substrates Ikaros and Aiolos (EC50s 1 and 0.5 nM) as well does not degrade GSPT1 or CK1a

Catalog No. 50-301-5856


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