Cayman Chemical AtractylenolIde III 10mg

Supplier:  Cayman Chemical 2491110 MG

A sesquiterpene; inhibits LPS-induced release of NO, PGE2, TNF-α, and IL-6 from RAW264.7 macrophages at 50 µM; induces apoptosis and cell-cycle arrest, as well as increases caspase-3, caspase-9, and PARP cleavage in A549 human lung carcinoma cells at 100 µM; inhibits glutamate-induced apoptosis and DNA fragmentation in primary embryonic mouse cerebral cortical neurons at 40 µM; inhibits induced angiogenesis in an MDA-MB-231 human breast cancer mouse xenograft model at 25 mg/kg per day; decreases the latency to find the platform in the Morris water maze in a rat model of high-dose homocysteine-induced learning deficits at 0.6 mg/kg per day

Catalog No. 50-301-5856