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Bachem Atrial Natriuretic Factor (1-28) (human) Trifluoroacetate

Supplier: Bachem 4011941.0500

Atrial Natriuretic Factor (1-28) (human) Trifluoroacetate, H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH, 89213-87-6, C127H203N45O39S3, Mr 3080.49, 0.5mg. Carperitide, ahANF, Atrial Natriuretic Peptide (ANP) (1-28) alpha, canine, human, ovine. ANP/ANF is synthesized in cardiac myocytes and is primarily released in response to atrial wall stretching and intravascular volume expansion. The peptide signals via the guanylate cyclase-linked natriuretic peptide receptor A (NPR-A) and plays an important role in blood pressure regulation and blood volume homeostasis. ANP/ANF exerts vasodilatory, diuretic, natriuretic, anti-inflammatory, antifibrotic and antimitogenic effects. As BNP, ANP stimulates lipolysis in adipocytes. Millucci et al. studied the aggregation behavior of aANP, which may play a role in congestive heart failure.
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