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Diagnostic Biosystems ATRX ATRX (D-5)
Supplier: Diagnostic Biosystems MOB600
ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATPdependent manner and facilitate the initiation of transcription and replication. Central nervous system (CNS): loss of ATRX expression in 45% of anaplastic astrocytomas, 27% of anaplastic oligoastrocytomas, 10% of anaplastic oligodendrogliomas. Genetic signatures, including ATRX, may refine classification of gliomas
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