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Medchemexpress LLC Auda | 479413-70-2 | 98.0% | 392.58 | 250 MG
Supplier: Medchemexpress LLC 250MGHY108570
AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 nM for mouse sEH and 69 nM for human sEH. It also exhibits anti-inflammatory activity.
- Potent soluble epoxide hydrolase (sEH) inhibitor.
- Ic50: 18 nM (mouse sEH) and 69 nM (human sEH).
- Possesses anti-inflammatory activity.
- Suppresses proliferation of rat VSMCs exposed to PDGF.
- Upregulates COX-2 expression.
- Augments migratory ability and increases adhesion ability of HCAECs.
- Reduces TNF-α, MMP-9, and IL-1β expression levels in vivo.
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