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Apexbio Technology LLC Aurora Kinase Inhibitor III 879127-16-9 1mg
Supplier: Apexbio Technology LLC B79471
Aurora Kinase Inhibitor III (CAS 879127-16-9) is a selective small molecule inhibitor targeting Aurora A kinase It acts by binding to the ATP-binding site of Aurora A thereby suppressing its enzymatic activity with an IC50 of 42 nM The compound exhibits substantially lower inhibitory potency against epidermal growth factor receptor (EGFR) with an IC50 greater than 10 M Aurora Kinase Inhibitor III serves as a useful chemical probe for investigating Aurora A-mediated processes including mitotic regulation cell cycle progression and associated signaling pathways and supports studies exploring the role of Aurora A in oncogenesis
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