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Cayman Chemical AurothIoglucosehydrate 10mg
Supplier: Cayman Chemical 3073210 MG
A TrxR inhibitor (IC50 = 0.065 µM for the human placental enzyme); selective for TrxR over glutathione reductase and GPX (IC50s = >100 and 80 µM, respectively); inhibits IL-1β-induced production of IL-6 and IL-8 in isolated human rheumatoid synovial fibroblasts at 100 µM; reduces HIV-1 replication induced by TNF-α in OM10.1 cells latently infected with HIV-1 at 10 and 25 µM; improves survival in a mouse model of ARDS induced by LPS and hyperoxia at 25 mg/kg; induces obesity and increases food intake and blood glucose levels in genetically diabetic KK mice
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