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Selleck Chemical LLC Luminespib (NVP-AUY922) 25mg 747412-49-3 AUY-922
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Supplier:  Selleck Chemical LLC S106925MG

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Luminespib (AUY-922, NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90?/? with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Luminespib (AUY-922, NVP-AUY922) effectively downregulates and destabilizes the IGF-1R? protein and results in growth inhibition, autophagy and apoptosis. Phase 2. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. 50-812-7


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