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Cayman Chemical Avagacestat, Purity: ≥98%, CAS: 1146699-66-2, 10 mg
SDP

Catalog No. 502967648
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A potent, orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP to Aβ40 than signaling through Notch (IC50s = 0.30 and 58 nM, respectively); shows good pharmacokinetics in rats, dogs, and humans and passes the blood-brain barrier, reducing plasma, brain, and cerebrospinal fluid Aβ40 levels

Catalog No. 50-296-7648 Supplier Cayman Chemical Supplier No. 1671110 MG
May include imposed supplier surcharges.
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A potent, orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP to Aβ40 than signaling through Notch (IC50s = 0.30 and 58 nM, respectively); shows good pharmacokinetics in rats, dogs, and humans and passes the blood-brain barrier, reducing plasma, brain, and cerebrospinal fluid Aβ40 levels

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