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Selleck Chemical LLC Avapritinib

Supplier: Selleck Chemical LLC S855325MG
Avapritinib is a small molecule kinase inhibitor that potently inhibits PDGFR D842V mutant activity in vitro (IC50 0 5 nM) and PDGFR D842V autophosphorylation in the cellular setting (IC50 30 nM) also a potent inhibitor of the analogous Kit (c-Kit) mutation D816V in Kit (c-Kit) Exon 17 (IC50 0 5 nM)
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