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Selleck Chemical LLC Avapritinib (BLU-285) 2mg 1703793-34-3
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Supplier:  Selleck Chemical LLC S85532MG

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Avapritinib (BLU-285) is a small molecule kinase inhibitor that potently inhibits PDGFR? D842V mutant activity in vitro (IC50 = 0.5 nM) and PDGFR? D842V autophosphorylation in the cellular setting (IC50 = 30 nM); also a potent inhibitor of the analogous Kit (c-Kit) mutation, D816V in Kit (c-Kit) Exon 17 (IC50 = 0.5 nM). *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. 50-194-8086


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