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Apexbio Technology LLC Avibactam sodium 1192491-61-4 50mg
Supplier: Apexbio Technology LLC B822750
Avibactam sodium (1192491-61-4) is a small-molecule inhibitor targeting bacterial -lactamase enzymes including CTX-M-15 and TEM-1 It is designed to inhibit -lactamase activity thereby preventing the hydrolysis of -lactam antibiotics Avibactam sodium exerts its biological activity primarily through reversible covalent non- -lactam inhibition of its targets In in vitro studies avibactam sodium demonstrates inhibitory activity with IC50 values of 5 nM for CTX-M-15 and 8 nM for TEM-1 Based on these pharmacological properties avibactam sodium holds research potential in studies of combination therapy for bacterial infections involving -lactamase-producing Gram-negative pathogens
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