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Medchemexpress LLC Aviptadil (acetate) | 1444827-29-5 | 99.8% | 3385.90 | 1 MG
SDP

Supplier:  Medchemexpress LLC HYP0012A1MG

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Aviptadil acetate is an analog of vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. It induces pulmonary vasodilation and inhibits vascular smooth muscle cell (SMC) proliferation and platelet aggregation. This compound is primarily utilized in research for conditions such as pulmonary fibrosis, pulmonary arterial hypertension (PAH), and respiratory failure caused by SARS-CoV-2.

  • Potent vasodilatory effects
  • Induces pulmonary vasodilation
  • Inhibits vascular smooth muscle cell proliferation and platelet aggregation
  • Used in research for pulmonary fibrosis, pulmonary arterial hypertension (PAH), and SARS-CoV-2 induced respiratory failure
  • Inhibits basal proliferation of pulmonary arterial smooth muscle cells (PASMC)
  • Reduces CSE-stimulated MMP activity and caspase-3 activation
  • Attenuates lipopolysaccharide (LPS)-induced MMP-9 activity by alveolar macrophages

Catalog No. 50-004-26355


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