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Medchemexpress LLC Avitinib maleate | 1557268-88-8 | 99.9% | 603.60 | 25 MG
SDP

Catalog No. 5000402668
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Avitinib maleate is a third-generation, irreversible, and orally active selective EGFR inhibitor. It has IC50 values of 0.18 nM against both EGFR L858R and EGFR T790M, and 7.68 nM against wild-type EGFR. It is also a BTK inhibitor, inducing apoptosis and inhibiting BTK phosphorylation in mantle cell lymphoma. It exhibits anticancer effects.

  • Third-generation, irreversible, and orally active selective EGFR inhibitor.
  • Potent against EGFR L858R, EGFR T790M, and wild-type EGFR.
  • BTK inhibitor.
  • Induces apoptosis.
  • Inhibits phosphorylation of BTK in mantle cell lymphoma.
  • Exhibits anticancer effects.

Catalog No. 50-004-02668 Supplier Medchemexpress LLC Supplier No. 25MGHY19816A
May include imposed supplier surcharges.
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Avitinib maleate is a third-generation, irreversible, and orally active selective EGFR inhibitor. It has IC50 values of 0.18 nM against both EGFR L858R and EGFR T790M, and 7.68 nM against wild-type EGFR. It is also a BTK inhibitor, inducing apoptosis and inhibiting BTK phosphorylation in mantle cell lymphoma. It exhibits anticancer effects.

  • Third-generation, irreversible, and orally active selective EGFR inhibitor.
  • Potent against EGFR L858R, EGFR T790M, and wild-type EGFR.
  • BTK inhibitor.
  • Induces apoptosis.
  • Inhibits phosphorylation of BTK in mantle cell lymphoma.
  • Exhibits anticancer effects.

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