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Eurofins Discoverx PathHunter AVPR1A Total GPCR Internalization U2OS Cell Line, 2 vials. (93-0751C3)
Supplier: Eurofins Discoverx 930751C3
The PathHunter AVPR1A Total GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of AVPR1A via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged AVPR1A and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the AVPR1A receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
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