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Cayman Chemical AZ 13705339 50mg
Supplier: Cayman Chemical 4208750 MG
A PAK1 inhibitor (IC50 = 0.33 nM); selective for PAK1 over a panel of 117 kinases at 100 nM; binds to PAK1 and PAK2 (Kd = 0.28 and 0.32 nM, respectively); inhibits S. enterica infection in HAP1 cells at 10 µM; inhibits cell death induced by an antibody targeting Siglec-8 in IL-5-stimulated primary human eosinophils (IC50 = 59 nM)
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