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Medchemexpress LLC Az12601011 | 2748337-86-0 | 99.8% | 50 MG
SDP

Supplier:  Medchemexpress LLC HY12285650MG

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AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor (also inhibits ALK4 and ALK7) used as a research reagent to study TGF-β signaling and tumor models. It inhibits SMAD2 phosphorylation with reported potency (IC50 18 nM; Kd 2.9 nM) and has shown antitumor activity in vivo. High-purity powder and DMSO stock solutions are available.

  • Selective TGFBR1, ALK4, and ALK7 inhibition.
  • Biochemical potency: IC50 18 nM; Kd 2.9 nM.
  • High purity (99.78%).
  • Available as powder and DMSO solution for in vitro studies.
  • Recommended storage: powder -20°C for long term, and solutions -80°C.

Catalog No. 50-002-30495


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