Azadibenzocyclooctyne acid

Description

CAS: 1425485-72-8 | C21H19NO3 | 333.39 g/mol

Azadibenzocyclooctyne acid is the simplest amine reactive reagent for introducing a dibenzylcyclooctyne to available amine functionality.Azadibenzocyclooctyne acid is widely useful in strain-promoted copper-free azide-alkyne click chemistry reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Azadibenzocyclooctyne acid is the simplest amine reactive reagent for introducing a dibenzylcyclooctyne to available amine functionality.Azadibenzocyclooctyne acid is widely useful in strain-promoted copper-free azide-alkyne click chemistry reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.

Solubility
Soluble in dimethyl sulfoxide and dimethyl formamide.

Notes
Store in cool place. Incompatible with amines.

Specifications

Chemical Identifiers

• CAS: 1425485-72-8
• Molecular Formula: C21H19NO3
• Molecular Weight (g/mol): 333.39
• MDL Number: MFCD22380737
• InChI Key: NIRLBCOFKPVQLM-UHFFFAOYSA-N
• Synonym: dbco-c6-acid, azadibenzocyclooctyne acid, dibenzocyclooctyne-acid, storage temp.:-20c, 6-11,12-didehydro-5,6-dihydrodibenzo b,f azocine-5-yl-6-oxohexanoic acid
• PubChem CID: 77078156

• Color: White to Gray
• Quantity: 100 mg
• Solubility Information: Soluble in dimethyl sulfoxide and dimethyl formamide.
• Formula Weight: 333.38
• Physical Form: Solid
• Chemical Name or Material: Azadibenzocyclooctyne acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only