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Abcam AZD-3965, 5MG
Supplier: Abcam AB2869585MG
MW 515.5 Da, Purity >=98%. A potent and selective monocarboxylate transporter 1 (MCT1) inhibitor with a binding affinity of 1.6 nM; it is 6-fold selective over MCT2 and does not inhibit MCT4 even at 10 μM. AZD 3965 increases intratumor lactate levels and decreases tumor growth in mice bearing COR-L103 small cell lung cancer (SCLC) xenografts.
The product is subject to the following: Abcam Restricted Use Statement
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