Apexbio Technology LLC AZD1152 722543-31-9 10mM (in 1mL DMSO)

Supplier:  Apexbio Technology LLC A32145.1

AZD1152 (CAS 722543-31-9) is a highly selective inhibitor of Aurora kinase a family of serine/threonine kinases involved in cancer cell proliferation It preferentially targets Aurora B kinase (IC50 0 37 nM) with lesser affinity toward Aurora A (IC50 1 37 M) and exhibits no notable activity against other kinases such as JAK2 FLT3 and Abl AZD1152 induces tumor cell cycle arrest in the G2/M phase triggers apoptosis and enhances radiosensitivity in androgen-resistant prostate cancer models In vivo AZD1152 demonstrates anti-tumor potency both alone and combined with chemotherapeutics or tubulin-targeting drugs offering a valuable research tool for oncology studies

Catalog No. 50-000-63024