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Selleck Chemical LLC Vistusertib (AZD2014) 5mg 1009298-59-2

Supplier: Selleck Chemical LLC S27835MG

Vistusertib (AZD2014) is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay; highly selective against multiple PI3K isoforms (?/?/?/?). AZD2014 showed no or weak binding to the majority of kinases when tested at 1 ?M. AZD2014 induces proliferation suppression, apoptosis, cell cycle arrest, and autophagy in HCC cells with antitumor activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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