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Selleck Chemical LLC AZD-5153 6-hydroxy-2-naphthoic acid 5mg 1869912-40-2 AZD-5153 HNT salt
Supplier: Selleck Chemical LLC S83445MG
AZD-5153 6-hydroxy-2-naphthoic acid (HNT salt) is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor with pKi of 8.3 for BRD4. AZD-5153 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes. NSD3, via H3K36me2, acts as an epigenetic deregulator to facilitate the expression of oncogenesis-promoting genes. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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