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Selleck Chemical LLC Selumetinib (AZD6244) 50mg 606143-52-6 ARRY-142886
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Supplier:  Selleck Chemical LLC S100850MG

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Selumetinib (AZD6244, ARRY-142886) is a potent, highly selective MEK inhibitor with IC50 of 14 nM for MEK1 and Kd value of 530 nM for MEK2. It also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38?, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Selumetinib suppresses cell proliferation, migration and trigger apoptosis. Phase 3. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. 50-871-1


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