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STEMCELL Technologies AZD8055, Size: 1 mg
Supplier: STEMCELL Technologies 73002
Selectively inhibit mammalian target of rapamycin (mTOR) with AZD8055 (Chresta et al. Cancer Res, 2010). This mTOR pathway inhibitor is widely used in cancer research to inhibit proliferation in different cancer cell lines, such as the A549 and H838 small-cell lung cancer cell lines (Chresta et al. Cancer Res, 2010), the Hep-2 human laryngeal cancer cell line (Zhao et al. Int J Clin Exp Med, 2014), and the HeLa human cervical cancer cell line (Li et al. Oncol Lett, 2013). In combination with ABT-737, AZD8055 induces apoptosis in rhabdomyosarcoma (RMS) cells (Preuss et al. J Biol Chem, 2013). It also inhibits cell proliferation, increases cell death, and reduces migration in tamoxifen-resistant and estrogen deprivation-resistant breast cancer cell lines (Jordan et al. Breast Cancer Res, 2014). AZD6244 is supplied as a crystalline solid with ≥98% purity; Molecular weight 465.5 g/mol; CAS Number 1009298-09-2. Visit STEMCELL.com for more information and related products.
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