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Selleck Chemical LLC AZD8421 E1972-1G
SDP

Catalog No. 5000039173
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AZD8421 is a potent and highly selective inhibitor of Cyclin-dependent Kinase 2 (CDK2) with an IC50 against CDK2 of 9nM with selectivity over CDK1 CDK4 and CDK6 It also exhibits an anti-proliferative effect effectively inhibits Rb phosphorylation and shows strong activity both as a monotherapy and in combination with CDK4/6 inhibitors in breast and ovarian cancer models

Catalog No. 50-000-39173 Supplier Selleck Chemical LLC Supplier No. E19721G
May include imposed supplier surcharges.
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AZD8421 is a potent and highly selective inhibitor of Cyclin-dependent Kinase 2 (CDK2) with an IC50 against CDK2 of 9nM with selectivity over CDK1 CDK4 and CDK6 It also exhibits an anti-proliferative effect effectively inhibits Rb phosphorylation and shows strong activity both as a monotherapy and in combination with CDK4/6 inhibitors in breast and ovarian cancer models

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