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Medchemexpress LLC AZD9056 hydrochloride | 345303-91-5 | 98.2% | 455.46 | 5 MG

Supplier: Medchemexpress LLC HY19427A5MG
AZD9056 hydrochloride is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases. It is for research use only.
- Selective orally active inhibitor of P2X7
- Plays a significant role in inflammation and pain-causing diseases
- Has a clear inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells
- Exerts pain-relieving and anti-inflammatory effects
- Reverses the upregulated expression of interleukin (IL)-1β, IL-6, tumor necrosis factor-α (TNF-α), matrix metalloproteinase-13 (MMP-13), substance P (SP) and prostaglandin E2 (PGE2) which is induced by MIA in cartilage tissues
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