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Apexbio Technology LLC Azelastine HCl 79307-93-0 200mg
Supplier: Apexbio Technology LLC B1568200
Azelastine HCl (79307-93-0) is a small-molecule antagonist targeting the histamine H1 receptor It is designed to inhibit the H1 receptor thereby disrupting histamine-induced inflammatory and allergic pathway signaling Azelastine HCl exerts its biological activity primarily through competitive antagonism of H1 receptors blocking downstream cascades including smooth muscle contraction increased endothelial permeability and inflammatory mediator release In receptor-binding studies Azelastine HCl demonstrates antagonist activity with IC50 values of approximately 1 2 2 5 nM Based on these pharmacological properties Azelastine HCl holds research potential in the investigation of allergy pathogenesis allergic inflammation mechanisms and the evaluation of receptor-specific responses in cellular and animal models
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