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Medchemexpress LLC Azide-PEG-amine | 95.0% | 25 MG
Supplier: Medchemexpress LLC 25MGHY140661
Azide-PEG-amine (MW 2000) is a PEG-based PROTAC linker, essential for synthesizing PROTACs. It acts as a versatile click chemistry reagent, featuring an azide group. This enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. PROTACs utilize this linker to connect ligands, targeting E3 ubiquitin ligase and a protein of interest for selective degradation. This product is for research use only.
- PEG-based PROTAC linker for PROTAC synthesis
- Functions as a click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC)
- Leverages ubiquitin-proteasome system for selective protein degradation
- Intended for research use only
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