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Medchemexpress LLC Azide-PEG-amine (MW 5000) | 95.0% | N₃(CH₂CH₂O)nNH₂ | 50 MG
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Supplier:  Medchemexpress LLC HY14066350MG

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Azide-PEG-amine (MW 5000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs utilize the ubiquitin-proteasome system to selectively degrade target proteins.

  • PEG-based PROTAC linker
  • Used in synthesis of PROTACs
  • Functions as a click chemistry reagent
  • Contains an azide group
  • Enables copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc)
  • Enables strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
  • Facilitates protein degradation via PROTACs
  • White to off-white solid appearance
  • Average molecular weight of 5000

Catalog No. 50-003-56453


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