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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | ≥97.0% | C22H46N4O10 | 250 MG
Supplier: Medchemexpress LLC 250MGHY140217
Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, enabling participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker for PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- PROTACs degrade target proteins via the ubiquitin-proteasome system
- Appearance is colorless to off-white
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