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Medchemexpress LLC Azido-PEG10-NHS ester | 2801772-86-9 | 98.0% | C27H48N4O14 | 100 MG
Supplier: Medchemexpress LLC HY140759100MG
Azido-PEG10-NHS ester is a versatile PEG-based PROTAC linker and click chemistry reagent. It contains an Azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This compound is instrumental in the synthesis of PROTACs, which leverage the intracellular ubiquitin-proteasome system for targeted protein degradation.
- Functions as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Contains an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Allows reactions with alkyne-containing molecules
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with molecules containing DBCO or BCN groups
- Aids in selective degradation of target proteins
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