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Medchemexpress LLC Azido-PEG2-C1-Boc | 251564-45-1 | >98% | C10H19N3O4 | 100 MG
Supplier: Medchemexpress LLC HY140793100MG
Azido-PEG2-C1-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent containing an Azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne group-containing molecules. It also facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs, composed of two different ligands connected by a linker, leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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