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Medchemexpress LLC Azido-PEG2-C2-Boc | 1271728-79-0 | 95.0% | C11H21N3O4 | 100 MG
Supplier: Medchemexpress LLC HY140776100MG
Azido-PEG2-C2-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules possessing Alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Serves as a PEG-based linker for PROTAC construction.
- Features an azide group enabling CuAAc reactions with alkyne-containing molecules.
- Capable of strain-promoted alkyne-azide cycloaddition with molecules containing DBCO or BCN groups.
- PROTACs leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
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