Azido-PEG3-biotin conjugate

Description

An azide-biotin conjugate with PEG spacer to improve solubility in aqueous media | CAS: 875770-34-6 | C18H32N6O5S | 444.551 g/mol

Biotinylation reagent for labeling alkyne containing molecules or biomolecules using either copper-catalyzed 1,3 dipolar cycloaddition click chemistry or copper-free click chemistry with cyclooctyne derivatives. The azide group reacts with alkynes to form a stable triazole linkage facilitating the introduction of biotin into your alkyne modified system of interest. This reaction is bioorthogonal or in other words compatible with biological systems in that it?s components do not react with the biological environment.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Biotinylation reagent for labeling alkyne containing molecules or biomolecules using either copper-catalyzed 1,3 dipolar cycloaddition click chemistry or copper-free click chemistry with cyclooctyne derivatives. The azide group reacts with alkynes to form a stable triazole linkage facilitating the introduction of biotin into your alkyne modified system of interest. This reaction is bioorthogonal or in other words compatible with biological systems in that it′s components do not react with the biological environment.

Solubility
Solubile in DMSO, DMF and water.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 875770-34-6
• Molecular Formula: C18H32N6O5S
• Molecular Weight (g/mol): 444.551
• MDL Number: MFCD20134145
• InChI Key: ZWFOOMQCYIGZBE-ZOBUZTSGSA-N
• Synonym: biotin-peg3-azide, n-2-2-2-2-azidoethoxy ethoxy ethoxy ethyl biotinamide, n-2-2-2-2-azidoethoxy ethoxy ethoxy ethyl-5-3as,4s,6ar-2-oxohexahydro-1h-thieno 3,4-d imidazol-4-yl pentanamide, biotin-peg4-n3, azide-peg3-biotin conjugate, azido-peg3-biotin conjugate, 11-r-+-biotinylamino-1-azido-3,6,9-trioxaundecane, 3abeta,6abeta-n-2-2-2-2-azidoethoxy ethoxy ethoxy ethyl-2-oxohexahydro-1h-thieno 3,4-d imidazole-4alpha-pentanamide
• PubChem CID: 60146223
• IUPAC Name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]pentanamide
• SMILES: C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-])NC(=O)N2

• Color: White to Gray
• Quantity: 25 mg
• Solubility Information: Solubile in DMSO,DMF and water.
• Formula Weight: 444.55
• Physical Form: Solid
• Chemical Name or Material: Azido-PEG3-biotin conjugate

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only