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Medchemexpress LLC Azido-PEG3-NHS ester | 1092654-47-1 | ≥98.0% | C12H18N4O7 | 250 MG
Supplier: Medchemexpress LLC 250MGHY140764
Azido-PEG3-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This compound is integral in the development of PROTACs, which harness the ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC)
- Enables selective degradation of target proteins
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