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Medchemexpress LLC Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane | 1421933-29-0 | 97.0% | C36H66N4O14 | 25 MG
Supplier: Medchemexpress LLC 25MGHY140874
This compound is a PEG-based PROTAC linker, instrumental in the synthesis of PROTACs. It also serves as a click chemistry reagent, featuring an azide group. This enables it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. PROTACs leverage an intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Exploits the ubiquitin-proteasome system for selective protein degradation
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