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Medchemexpress LLC Azido-PEG4-Amido-Tris | 1398044-55-7 | 96.4% | C15H30N4O8 | 100 MG
Supplier: Medchemexpress LLC HY141249100MG
Azido-PEG4-Amido-Tris is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules possessing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs involve two distinct ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group for CuAAc reaction
- Can undergo SPAAC reactions
- Used in the synthesis of PROTACs
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