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Medchemexpress LLC Azido-PEG6-NHS ester | 2055014-64-5 | 98.0% | 1 G
Supplier: Medchemexpress LLC HY1304741G
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It also functions as a PEG- and Alkyl/ether based PROTAC linker for synthesizing PROTACs. This compound is a click chemistry reagent, featuring an Azide group, which allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Cleavable linker
- PEG linker type
- Alkyl/ether linker type
- Click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions
- Undergoes strain-promoted alkyne-azide cycloaddition reactions
- Used in ADC synthesis
- Used in PROTAC synthesis
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