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Medchemexpress LLC Azidoethyl-SS-PEG2-Boc | 2144777-83-1 | 351.49 | 250 MG
Supplier: Medchemexpress LLC 250MGHY140107
Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
- PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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