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Medchemexpress LLC AZP-531 | 1088543-62-7 | 99.8% | 962.02 | 1 MG
Supplier: Medchemexpress LLC HYP02311MG
AZP-531 is an analogue of unacylated ghrelin for research use, designed to improve glycaemic control and reduce weight. It shows survival effects on pancreatic β-cells and human pancreatic islets, and is highly stable in human plasma in vitro with no degradation after one day at 37°C.
- Exhibits survival effects on pancreatic β-cells and human pancreatic islets.
- Stable in human plasma in vitro at 37°C for one day.
- Prevents high-fat diet-induced weight gain, proinflammatory effects, and prediabetic metabolic state in mice.
- Stimulates mitochondrial function markers in brown adipose tissue.
- Well-tolerated in clinical trials; improves glucose without increasing insulin.
- Reduces mean body weight and HbA1c in clinical trials.
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