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Cayman Chemical AzurIn50-77PaerugInosa 10mg

Supplier: Cayman Chemical 3672510 MG
A peptide; inhibitor of VEGFR2 (IC20 = ~10.7 µM); induces cell cycle arrest at the G2/M phase in MCF-7 cells at 20 µM; reduces MCF-7 and ZR-75-1 cancer cell proliferation at 50 µM; reduces VEGF-A-induced capillary tube formation (IC50 = 12 µM), as well as decreases cell-membrane associated levels of F-actin, FAK, and paxillin and increases extracellular levels of PECAM-1 in HUVECs at 25 µM; reduces tumor volume in an MCF-7 mouse xenograft model at 10 mg/kg per day
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