Learn More
Medchemexpress LLC B I09 | 1607803-67-7 | 99.4% | 303.31 g/mol | C16H17NO5 | 100 MG

Supplier: Medchemexpress LLC HY107400100MG
B I09 is a small-molecule inhibitor of the IRE-1 RNase with a reported in vitro IC50 of 1,230 nM. It inhibits splicing of XBP1 mRNA and reduces expression of XBP-1s in cellular assays, and is used to probe IRE-1-mediated unfolded protein response signaling. The compound is a light yellow to brown solid, soluble in DMSO, and unstable in solution so solutions should be freshly prepared.
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.